1187917-12-9 → HCID 44230124, compound

HRID 1949282Notes

Reaction equation

HRID 1949282 reaction equation
ClC1C=C(N2C(C3C=CC=C(Cl)C=3)=CC(C(O)=O)=N2)C=CC=1.[Cl:23][C:24]1[CH:25]=[C:26]([N:31]2[C:35]([C:36]3[CH:41]=[C:40](F)[CH:39]=[C:38]([Cl:43])[CH:37]=3)=[CH:34][C:33]([C:44]([N:46]3[CH2:50][C:49](=[O:51])[NH:48][CH2:47]3)=[O:45])=[N:32]2)[CH:27]=[CH:28][C:29]=1F>>[Cl:23][C:24]1[CH:25]=[C:26]([N:31]2[C:35]([C:36]3[CH:41]=[CH:40][CH:39]=[C:38]([Cl:43])[CH:37]=3)=[CH:34][C:33]([C:44]([N:46]3[CH2:50][C:49](=[O:51])[NH:48][CH2:47]3)=[O:45])=[N:32]2)[CH:27]=[CH:28][CH:29]=1

Participants

3

Reactant 2

HCID 442301811187917-12-9HCID 58277345HCID 58277345, compound

Product 1

HCID 44230124HCID 44230124, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 74A in analogy to the synthesis of the compound of Example 1. 110 mg (91% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-c4005767797444d495652a99414aff02
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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