1187917-12-9 → HCID 58277272, compound

HRID 1949283Notes

Reaction equation

HRID 1949283 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13]([C:14]3[CH:19]=[CH:18][C:17]([F:20])=[C:16]([Cl:21])[CH:15]=3)=[CH:12][C:11]([C:22](O)=[O:23])=[N:10]2)[CH:5]=[CH:6][C:7]=1[F:8].ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C([N:48]3[CH2:52][C:51](=[O:53])[NH:50][CH2:49]3)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13]([C:14]3[CH:19]=[CH:18][C:17]([F:20])=[C:16]([Cl:21])[CH:15]=3)=[CH:12][C:11]([C:22]([N:48]3[CH2:52][C:51](=[O:53])[NH:50][CH2:49]3)=[O:23])=[N:10]2)[CH:5]=[CH:6][C:7]=1[F:8]

Participants

3

Reactant 2

HCID 442301811187917-12-9HCID 58277316HCID 58277316, compound

Product 1

HCID 58277272HCID 58277272, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 75A in analogy to the synthesis of the compound of Example 1. 23 mg (39% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-d95054bc80fc45fab8b8df955ae2fa0b
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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