1187917-12-9 → HCID 58277304, compound

HRID 1949284Notes

Reaction equation

HRID 1949284 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([O:19][C:20]([F:23])([F:22])[F:21])[CH:14]=3)=[CH:11][C:10]([C:24]([OH:26])=O)=[N:9]2)[CH:5]=[CH:6][CH:7]=1.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C([N:50]3[CH2:54][C:53](=[O:55])[NH:52][CH2:51]3)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([O:19][C:20]([F:22])([F:21])[F:23])[CH:14]=3)=[CH:11][C:10]([C:24]([N:50]3[CH2:54][C:53](=[O:55])[NH:52][CH2:51]3)=[O:26])=[N:9]2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 442301811187917-12-9HCID 58277445HCID 58277445, compound

Product 1

HCID 58277304HCID 58277304, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 76A in analogy to the synthesis of the compound of Example 1. 24 mg (64% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-b0389fd526eb4878b6ca745bbf630a14
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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