1187917-12-9 → HCID 44230183, compound

HRID 1949285Notes

Reaction equation

HRID 1949285 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][C:16]([F:19])=[C:15]([C:20]([F:23])([F:22])[F:21])[CH:14]=3)=[CH:11][C:10]([C:24]([OH:26])=O)=[N:9]2)[CH:5]=[CH:6][CH:7]=1.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C([N:50]3[CH2:54][C:53](=[O:55])[NH:52][CH2:51]3)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][C:16]([F:19])=[C:15]([C:20]([F:21])([F:23])[F:22])[CH:14]=3)=[CH:11][C:10]([C:24]([N:50]3[CH2:54][C:53](=[O:55])[NH:52][CH2:51]3)=[O:26])=[N:9]2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 442301811187917-12-9HCID 58277417HCID 58277417, compound

Product 1

HCID 44230183HCID 44230183, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 77A in analogy to the synthesis of the compound of Example 1. 28 mg (74% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-fdfdf10ec16a490a93300b17a9127b41
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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