1187917-12-9 → HCID 58277439, compound

HRID 1949287Notes

Reaction equation

HRID 1949287 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[N:13]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([Cl:20])[CH:15]=3)[N:12]=[C:11]([C:21](O)=[O:22])[CH:10]=2)[CH:5]=[CH:6][C:7]=1[F:8].ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C([N:47]3[CH2:51][C:50](=[O:52])[NH:49][CH2:48]3)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[N:13]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([Cl:20])[CH:15]=3)[N:12]=[C:11]([C:21]([N:47]3[CH2:51][C:50](=[O:52])[NH:49][CH2:48]3)=[O:22])[CH:10]=2)[CH:5]=[CH:6][C:7]=1[F:8]

Participants

3

Reactant 2

HCID 442301811187917-12-9HCID 58277283HCID 58277283, compound

Product 1

HCID 58277439HCID 58277439, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 79A in analogy to the synthesis of the compound of Example 1. 52 mg (87% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-926cbca07b444c33aa3ee16ed41ac5e1
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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