1187917-12-9 → HCID 58277270, compound

HRID 1949288Notes

Reaction equation

HRID 1949288 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([C:8]2[N:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH3:20])[CH:14]=3)[N:11]=[C:10]([C:21](O)=[O:22])[CH:9]=2)[CH:5]=[CH:6][CH:7]=1.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C([N:47]3[CH2:51][C:50](=[O:52])[NH:49][CH2:48]3)=O)=N2)C=CC=1F>>[F:1][C:2]1[CH:3]=[C:4]([C:8]2[N:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH3:20])[CH:14]=3)[N:11]=[C:10]([C:21]([N:47]3[CH2:51][C:50](=[O:52])[NH:49][CH2:48]3)=[O:22])[CH:9]=2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 442301811187917-12-9HCID 58277379HCID 58277379, compound

Product 1

HCID 58277270HCID 58277270, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 80A in analogy to the synthesis of the compound of Example 1. 27 mg (70% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-9ae0dc65566c40b7b6b57f0e3bc8c2d4
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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