1187917-12-9 → HCID 58277343, compound

HRID 1949289Notes

Reaction equation

HRID 1949289 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH3:20])[CH:14]=3)=[CH:11][C:10]([C:21]([OH:23])=O)=[N:9]2)[CH:5]=[CH:6][CH:7]=1.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C([N:47]3[CH2:51][C:50](=[O:52])[NH:49][CH2:48]3)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH3:20])[CH:14]=3)=[CH:11][C:10]([C:21]([N:47]3[CH2:51][C:50](=[O:52])[NH:49][CH2:48]3)=[O:23])=[N:9]2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 442301811187917-12-9HCID 58277425HCID 58277425, compound

Product 1

HCID 58277343HCID 58277343, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 81A in analogy to the synthesis of the compound of Example 1. 31 mg (84% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-7077255657ec415f84995022c0d261d8
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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