1187917-12-9 → HCID 58277384, compound

HRID 1949290Notes

Reaction equation

HRID 1949290 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[N:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([C:19]([F:22])([F:21])[F:20])[CH:14]=3)[N:11]=[C:10]([C:23]([OH:25])=O)[CH:9]=2)[CH:5]=[CH:6][CH:7]=1.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C([N:49]3[CH2:53][C:52](=[O:54])[NH:51][CH2:50]3)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[N:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([C:19]([F:20])([F:21])[F:22])[CH:14]=3)[N:11]=[C:10]([C:23]([N:49]3[CH2:53][C:52](=[O:54])[NH:51][CH2:50]3)=[O:25])[CH:9]=2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 442301811187917-12-9HCID 58277328HCID 58277328, compound

Product 1

HCID 58277384HCID 58277384, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 82A in analogy to the synthesis of the compound of Example 1. 22 mg (58% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-db6a4679d6314385a67e2bc709c4cd38
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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