1187917-12-9 → HCID 58277282, compound

HRID 1949291Notes

Reaction equation

HRID 1949291 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][C:16]([F:19])=[C:15]([F:20])[CH:14]=3)=[CH:11][C:10]([C:21](O)=[O:22])=[N:9]2)[CH:5]=[CH:6][CH:7]=1.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C([N:47]3[CH2:51][C:50](=[O:52])[NH:49][CH2:48]3)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][C:16]([F:19])=[C:15]([F:20])[CH:14]=3)=[CH:11][C:10]([C:21]([N:47]3[CH2:51][C:50](=[O:52])[NH:49][CH2:48]3)=[O:22])=[N:9]2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 442301811187917-12-9HCID 58277418HCID 58277418, compound

Product 1

HCID 58277282HCID 58277282, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 83A in analogy to the synthesis of the compound of Example 1. 16 mg (41% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-b05f633157a9494db44a5b71827b8321
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

Loading…