1187917-12-9 → HCID 58277350, compound

HRID 1949292Notes

Reaction equation

HRID 1949292 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([C:9]2[N:13]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([Cl:20])[CH:15]=3)[N:12]=[C:11]([C:21]([OH:23])=O)[CH:10]=2)[CH:5]=[CH:6][C:7]=1[F:8].ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C([N:47]3[CH2:51][C:50](=[O:52])[NH:49][CH2:48]3)=O)=N2)C=CC=1F>>[Br:1][C:2]1[CH:3]=[C:4]([C:9]2[N:13]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([Cl:20])[CH:15]=3)[N:12]=[C:11]([C:21]([N:47]3[CH2:51][C:50](=[O:52])[NH:49][CH2:48]3)=[O:23])[CH:10]=2)[CH:5]=[CH:6][C:7]=1[F:8]

Participants

3

Reactant 2

HCID 442301811187917-12-9HCID 58277288HCID 58277288, compound

Product 1

HCID 58277350HCID 58277350, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 84A in analogy to the synthesis of the compound of Example 1. 26 mg (70% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-d6758db7114c4489a01eeeb1b506dc97
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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