1187917-12-9 → HCID 58277444, compound

HRID 1949293Notes

Reaction equation

HRID 1949293 reaction equation
ClC1C=C(C2N(C3C=CC(F)=CC=3)N=C(C(O)=O)C=2)C=CC=1.Cl[C:24]1[CH:25]=[C:26]([N:31]2[C:35]([C:36]3[CH:41]=[C:40](F)[CH:39]=[C:38]([Cl:43])[CH:37]=3)=[CH:34][C:33]([C:44]([N:46]3[CH2:50][C:49](=[O:51])[NH:48][CH2:47]3)=[O:45])=[N:32]2)[CH:27]=[CH:28][C:29]=1[F:30]>>[Cl:43][C:38]1[CH:37]=[C:36]([C:35]2[N:31]([C:26]3[CH:25]=[CH:24][C:29]([F:30])=[CH:28][CH:27]=3)[N:32]=[C:33]([C:44]([N:46]3[CH2:50][C:49](=[O:51])[NH:48][CH2:47]3)=[O:45])[CH:34]=2)[CH:41]=[CH:40][CH:39]=1

Participants

3

Reactant 2

HCID 442301811187917-12-9HCID 58277393HCID 58277393, compound

Product 1

HCID 58277444HCID 58277444, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 85A in analogy to the synthesis of the compound of Example 1. 53 mg (42% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-787d2641ef734030a81987c62b0b6dcd
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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