1187917-12-9 → HCID 58277415, compound

HRID 1949294Notes

Reaction equation

HRID 1949294 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=3[F:19])=[CH:11][C:10]([C:20]([OH:22])=O)=[N:9]2)[CH:5]=[CH:6][CH:7]=1.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C([N:46]3[CH2:50][C:49](=[O:51])[NH:48][CH2:47]3)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=3[F:19])=[CH:11][C:10]([C:20]([N:46]3[CH2:50][C:49](=[O:51])[NH:48][CH2:47]3)=[O:22])=[N:9]2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 442301811187917-12-9HCID 58277359HCID 58277359, compound

Product 1

HCID 58277415HCID 58277415, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 86A in analogy to the synthesis of the compound of Example 1. 34 mg (88% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-2bd76d676f1749058f0472e4b2af3d00
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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