1187917-12-9 → HCID 44230317, compound

HRID 1949295Notes

Reaction equation

HRID 1949295 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([C:19]([F:22])([F:21])[F:20])[CH:14]=3)=[CH:11][C:10]([C:23]([OH:25])=O)=[N:9]2)=[CH:4][CH:3]=1.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C([N:49]3[CH2:53][C:52](=[O:54])[NH:51][CH2:50]3)=O)=N2)C=CC=1F>>[F:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([C:19]([F:20])([F:21])[F:22])[CH:14]=3)=[CH:11][C:10]([C:23]([N:49]3[CH2:53][C:52](=[O:54])[NH:51][CH2:50]3)=[O:25])=[N:9]2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 442301811187917-12-9HCID 58277279HCID 58277279, compound

Product 1

HCID 44230317HCID 44230317, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 87A in analogy to the synthesis of the compound of Example 1. 28 mg (74% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-3a2ba18a6716411286ca6a33ce123ee4
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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