1187917-12-9 → HCID 58277399, compound

HRID 1949296Notes

Reaction equation

HRID 1949296 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([F:19])[C:14]=3[F:20])=[CH:11][C:10]([C:21]([OH:23])=O)=[N:9]2)[CH:5]=[CH:6][CH:7]=1.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C([N:47]3[CH2:51][C:50](=[O:52])[NH:49][CH2:48]3)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([F:19])[C:14]=3[F:20])=[CH:11][C:10]([C:21]([N:47]3[CH2:51][C:50](=[O:52])[NH:49][CH2:48]3)=[O:23])=[N:9]2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 442301811187917-12-9HCID 58277416HCID 58277416, compound

Product 1

HCID 58277399HCID 58277399, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 88A in analogy to the synthesis of the compound of Example 1. 8 mg (100% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-0f487cad49374c17b4043d83f86524a7
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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