1187917-12-9 → HCID 58277356, compound

HRID 1949297Notes

Reaction equation

HRID 1949297 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[N:12]([C:13]3[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][CH:14]=3)[N:11]=[C:10]([C:20]([OH:22])=O)[CH:9]=2)[CH:5]=[CH:6][CH:7]=1.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C([N:46]3[CH2:50][C:49](=[O:51])[NH:48][CH2:47]3)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[N:12]([C:13]3[CH:14]=[CH:15][C:16]([Cl:19])=[CH:17][CH:18]=3)[N:11]=[C:10]([C:20]([N:46]3[CH2:50][C:49](=[O:51])[NH:48][CH2:47]3)=[O:22])[CH:9]=2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 442301811187917-12-9HCID 58277276HCID 58277276, compound

Product 1

HCID 58277356HCID 58277356, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 89A in analogy to the synthesis of the compound of Example 1. 31 mg (80% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-239a9b0c040342fe94da11ada9187328
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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