1187917-12-9 → HCID 58277405, compound

HRID 1949298Notes

Reaction equation

HRID 1949298 reaction equation
FC1C=C(C2N(C3C=CC(F)=CC=3)N=C(C(O)=O)C=2)C=CC=1.Cl[C:24]1[CH:25]=[C:26]([N:31]2[C:35]([C:36]3[CH:41]=[C:40]([F:42])[CH:39]=[C:38](Cl)[CH:37]=3)=[CH:34][C:33]([C:44]([N:46]3[CH2:50][C:49](=[O:51])[NH:48][CH2:47]3)=[O:45])=[N:32]2)[CH:27]=[CH:28][C:29]=1[F:30]>>[F:42][C:40]1[CH:41]=[C:36]([C:35]2[N:31]([C:26]3[CH:25]=[CH:24][C:29]([F:30])=[CH:28][CH:27]=3)[N:32]=[C:33]([C:44]([N:46]3[CH2:50][C:49](=[O:51])[NH:48][CH2:47]3)=[O:45])[CH:34]=2)[CH:37]=[CH:38][CH:39]=1

Participants

3

Reactant 2

HCID 442301811187917-12-9HCID 58277404HCID 58277404, compound

Product 1

HCID 58277405HCID 58277405, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 90A in analogy to the synthesis of the compound of Example 1. 18 mg (47% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-181e4b95776c49349cf6ef61b3e26031
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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