HCID 58277360, compound → HCID 58277397, compound

HRID 1949300Notes

Reaction equation

HRID 1949300 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH2:20][CH2:21][CH2:22][OH:23])[CH:14]=3)=[CH:11][C:10]([C:24]([OH:26])=O)=[N:9]2)[CH:5]=[CH:6][CH:7]=1.ClC1C=C(N2C(C3C=CC=C(OCCO)C=3)=CC(C([N:51]3[CH2:55][C:54](=[O:56])[NH:53][CH2:52]3)=O)=N2)C=CC=1>>[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH2:20][CH2:21][CH2:22][OH:23])[CH:14]=3)=[CH:11][C:10]([C:24]([N:51]3[CH2:55][C:54](=[O:56])[NH:53][CH2:52]3)=[O:26])=[N:9]2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 58277360HCID 58277360, compoundHCID 58277461HCID 58277461, compound

Product 1

HCID 58277397HCID 58277397, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 116A in analogy to the synthesis of the compound of Example 23. 54 mg (69% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-29f6f0b917c04dc4ada68c627054f9d8
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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