HCID 58277360, compound → HCID 58277338, compound

HRID 1949301Notes

Reaction equation

HRID 1949301 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13]([C:14]3[CH:19]=[C:18]([C:20]([F:23])([F:22])[F:21])[CH:17]=[C:16]([F:24])[CH:15]=3)=[CH:12][C:11]([C:25]([OH:27])=O)=[N:10]2)[CH:5]=[CH:6][C:7]=1[F:8].ClC1C=C(N2C(C3C=CC=C(OCCO)C=3)=CC(C([N:52]3[CH2:56][C:55](=[O:57])[NH:54][CH2:53]3)=O)=N2)C=CC=1>>[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13]([C:14]3[CH:19]=[C:18]([C:20]([F:22])([F:23])[F:21])[CH:17]=[C:16]([F:24])[CH:15]=3)=[CH:12][C:11]([C:25]([N:52]3[CH2:56][C:55](=[O:57])[NH:54][CH2:53]3)=[O:27])=[N:10]2)[CH:5]=[CH:6][C:7]=1[F:8]

Participants

3

Reactant 2

HCID 58277360HCID 58277360, compoundHCID 58277427HCID 58277427, compound

Product 1

HCID 58277338HCID 58277338, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 96A in analogy to the synthesis of the compound of Example 23. 17 mg (27% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-7c0db59a3c5c4e7fa9bcb7184e7649c0
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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