HCID 58277360, compound → HCID 67153489, compound

HRID 1949304Notes

Reaction equation

HRID 1949304 reaction equation
ClC1C=C(N2C(C3C=CC=C(OCC[CH2:22][N:23]4[CH2:27][CH2:26][CH2:25][CH2:24]4)C=3)=CC([C:28]([OH:30])=[O:29])=N2)C=CC=1.[Cl:31][C:32]1[CH:33]=[C:34]([N:38]2[C:42]([C:43]3[CH:48]=[CH:47][CH:46]=[C:45]([O:49][CH2:50][CH2:51]O)[CH:44]=3)=[CH:41][C:40]([C:53]([N:55]3[CH2:59][C:58](=[O:60])[NH:57][CH2:56]3)=[O:54])=[N:39]2)[CH:35]=[CH:36][CH:37]=1>>[CH:28]([OH:30])=[O:29].[Cl:31][C:32]1[CH:33]=[C:34]([N:38]2[C:42]([C:43]3[CH:48]=[CH:47][CH:46]=[C:45]([O:49][CH2:50][CH2:51][CH2:22][N:23]4[CH2:27][CH2:26][CH2:25][CH2:24]4)[CH:44]=3)=[CH:41][C:40]([C:53]([N:55]3[CH2:59][C:58](=[O:60])[NH:57][CH2:56]3)=[O:54])=[N:39]2)[CH:35]=[CH:36][CH:37]=1

Participants

3

Reactant 2

HCID 58277360HCID 58277360, compoundHCID 58277432HCID 58277432, compound

Product 1

HCID 67153489HCID 67153489, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 118A in analogy to the synthesis of the compound of Example 23. 3.2 mg (33% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-73850d86022f41259914e121b30098dc
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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