HCID 58277358, compound → HCID 58277421, compound

HRID 1949305Notes

Reaction equation

HRID 1949305 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([Cl:19])[CH:14]=3)=[CH:11][C:10]([C:20](O)=[O:21])=[N:9]2)[CH:5]=[CH:6][CH:7]=1.ClC1C=C(N2C(C3C=CC=C(OCCO)C=3)=CC(C([N:47]3[CH2:51][C:50](=[O:52])[NH:49][CH2:48]3)=O)=N2)C=CC=1>>[Br:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([Cl:19])[CH:14]=3)=[CH:11][C:10]([C:20]([N:47]3[CH2:51][C:50](=[O:52])[NH:49][CH2:48]3)=[O:21])=[N:9]2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 58277358HCID 58277358, compoundHCID 58277360HCID 58277360, compound

Product 1

HCID 58277421HCID 58277421, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 98A in analogy to the synthesis of the compound of Example 23. 122 mg (52% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-067715ab606049e4b799376dd584fb4d
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

Loading…