HCID 58277360, compound → HCID 58277290, compound

HRID 1949306Notes

Reaction equation

HRID 1949306 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][C:16]([F:19])=[C:15]([Cl:20])[CH:14]=3)=[CH:11][C:10]([C:21]([OH:23])=O)=[N:9]2)[CH:5]=[CH:6][CH:7]=1.ClC1C=C(N2C(C3C=CC=C(OCCO)C=3)=CC(C([N:48]3[CH2:52][C:51](=[O:53])[NH:50][CH2:49]3)=O)=N2)C=CC=1>>[Br:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][C:16]([F:19])=[C:15]([Cl:20])[CH:14]=3)=[CH:11][C:10]([C:21]([N:48]3[CH2:52][C:51](=[O:53])[NH:50][CH2:49]3)=[O:23])=[N:9]2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 58277360HCID 58277360, compoundHCID 58277435HCID 58277435, compound

Product 1

HCID 58277290HCID 58277290, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 99A in analogy to the synthesis of the compound of Example 23. 186 mg (79% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-b212e11ded3e43b497fc0ad1a0fed180
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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