HCID 58277360, compound → HCID 58277294, compound

HRID 1949308Notes

Reaction equation

HRID 1949308 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([O:20][CH3:21])[CH:15]=3)=[CH:12][C:11]([C:22](O)=[O:23])=[N:10]2)[CH:5]=[CH:6][C:7]=1[F:8].ClC1C=C(N2C(C3C=CC=C(OCCO)C=3)=CC(C([N:49]3[CH2:53][C:52](=[O:54])[NH:51][CH2:50]3)=O)=N2)C=CC=1>>[Cl:1][C:2]1[CH:3]=[C:4]([N:9]2[C:13]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([O:20][CH3:21])[CH:15]=3)=[CH:12][C:11]([C:22]([N:49]3[CH2:53][C:52](=[O:54])[NH:51][CH2:50]3)=[O:23])=[N:10]2)[CH:5]=[CH:6][C:7]=1[F:8]

Participants

3

Reactant 2

HCID 58277360HCID 58277360, compoundHCID 58277424HCID 58277424, compound

Product 1

HCID 58277294HCID 58277294, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 102A in analogy to the synthesis of the compound of Example 23. 7 mg (12% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-f7abaf6452084b008b581e563050a73c
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

Loading…