1187917-12-9 → HCID 58277420, compound

HRID 1949319Notes

Reaction equation

HRID 1949319 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([F:19])[CH:14]=3)=[CH:11][C:10]([C:20]([OH:22])=O)=[N:9]2)=[CH:4][CH:3]=1.ClC1C=C(N2C(C3C=C(F)C=C(Cl)C=3)=CC(C([N:46]3[CH2:50][C:49](=[O:51])[NH:48][CH2:47]3)=O)=N2)C=CC=1F>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([F:19])[CH:14]=3)=[CH:11][C:10]([C:20]([N:46]3[CH2:50][C:49](=[O:51])[NH:48][CH2:47]3)=[O:22])=[N:9]2)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 442301811187917-12-9HCID 58277349HCID 58277349, compound

Product 1

HCID 58277420HCID 58277420, compound

Procedure

The preparation of the title compound takes place starting from the compound of Example 105A in analogy to the synthesis of the compound of Example 1. 15 mg (39% of theory) of the title compound are obtained.

Sources & evidence

ORD record
ord-5b73096cb6cc4b8887022f90734bdf8b
Source dataset
uspto-grants-2013_03
Patent number
US08399682B2

Reaction notes

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