HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl tetrafluoro-2-(trifluoromethyl)propionate → HCID 86605061, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl tetrafluoro-2-(trifluoromethyl)propionate | HCID 2775518 | — |
| Reactant | HCID 19105657 | HCID 19105657 | — |
| Reactant | HCID 178418443 | HCID 178418443 | — |
| Product | HCID 86605061 | HCID 86605061 | — |
Reaction Steps
1,1,1,2-Tetrafluoro-2-(trifluoromethyl)-pentane ((CF3)2CFCH2CH2CH3) may be prepared by reacting methyl perfluoroisobutyrate with ethyl magnesium bromide followed by hydrolysis to give 1,1,1,2-tetrafluoro-2-(trifluoromethyl)-3-pentanol. The pentanol is converted to 4,5,5,5-tetrafluoro-4-(trifluoromethyl)-2-pentene by dehydration with phosphorous pentoxide and the double bond saturated by hydrogenation over a palladium on carbon catalyst.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399723B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-cbfe8202b73d451db15451b5470822eb |
| Source note | uspto-grants-2013_03 |