2,4-Bis(trifluoromethyl)benzyl bromide → 1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazole-5-carbaldehyde

HRID 1949336ノート

反応式

HRID 1949336 の反応式
[NH:1]1[C:9]2[C:4](=[CH:5][C:6]([CH:10]=[O:11])=[CH:7][CH:8]=2)[CH:3]=[N:2]1.Br[CH2:13][C:14]1[CH:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][C:15]=1[C:24]([F:27])([F:26])[F:25]>>[F:25][C:24]([F:26])([F:27])[C:15]1[CH:16]=[C:17]([C:20]([F:23])([F:21])[F:22])[CH:18]=[CH:19][C:14]=1[CH2:13][N:1]1[C:9]2[C:4](=[CH:5][C:6]([CH:10]=[O:11])=[CH:7][CH:8]=2)[CH:3]=[N:2]1

参加物

3

反応物 2

HCID 5188712,4-Bis(trifluoromethyl)benzyl bromideHCID 212506441H-Indazole-5-carboxaldehyde

生成物 1

HCID 866545381-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazole-5-carbaldehyde

実験手順

1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazole-5-carbaldehyde was prepared from 1H-Indazole-5-carbaldehyde and 1-bromomethyl-2,4-bis-trifluoromethyl-benzene following General Procedure A.

出典と根拠

ORDレコード
ord-69faebe256bd46f7b5d0d60520dc32f8
出典データセット
uspto-grants-2013_03
特許番号
US08399681B2

反応ノート

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