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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1949343Generated: November 1, 2026

1-(2-Hydroxyethyl)piperazine → HCID 86654545, compound

https://huagongshe.com/reaction/1949343

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Hydroxyethyl)piperazineHCID 7677—
Reactant5-[1-(2,4-bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]2-methylsulfanyl-thiazol-4-oneHCID 86654543—
ProductHCID 86654545HCID 86654545—

Reaction Steps

5-[1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-[4-(2-hydroxy-ethyl)-piperazin-1-yl]-thiazol-4-one was prepared from 5-[1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-methylsulfanyl-thiazol-4-one and 2-piperazin-1-yl-ethanol following General Procedure C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399681B2
Source datasetuspto-grants-2013_03
ORD IDord-b402a9d0cd7a40879d524d867750dc12
Source noteuspto-grants-2013_03