1H-Indazole-5-carboxaldehyde → HCID 86654548, compound

HRID 1949347Notes

Reaction equation

HRID 1949347 reaction equation
Br[CH2:2][C:3]1[CH:10]=[CH:9][C:6]([C:7]#[N:8])=[CH:5][C:4]=1[C:11]([F:14])([F:13])[F:12].[NH:15]1[C:23]2[C:18](=[CH:19][C:20]([CH:24]=[O:25])=[CH:21][CH:22]=2)[CH:17]=[N:16]1>>[CH:24]([C:20]1[CH:19]=[C:18]2[C:23](=[CH:22][CH:21]=1)[N:15]([CH2:2][C:3]1[CH:10]=[CH:9][C:6]([C:7]#[N:8])=[CH:5][C:4]=1[C:11]([F:14])([F:13])[F:12])[N:16]=[CH:17]2)=[O:25]

Participants

3

Reactant 2

HCID 212506441H-Indazole-5-carboxaldehydeHCID 588271604-(bromomethyl)-3-(trifluoromethyl)benzonitrile

Product 1

HCID 86654548HCID 86654548, compound

Procedure

4-(5-Formyl-indazol-1-ylmethyl)-3-trifluoromethyl-benzonitrile was prepared from 4-bromomethyl-3-trifluoromethyl-benzonitrile and 1H-indazole-5-carbaldehyde following General Procedure A.

Sources & evidence

ORD record
ord-e6586990e05e48bf82fa20b959966542
Source dataset
uspto-grants-2013_03
Patent number
US08399681B2

Reaction notes

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