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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1949385Generated: October 28, 2026

D-Proline → HCID 86654558, compound

https://huagongshe.com/reaction/1949385

Reaction equation

Participants

RoleNameHCIDCharge
ReactantD-ProlineHCID 8988—
Reactant5-[1-(2,4-bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]2-methylsulfanyl-thiazol-4-oneHCID 86654543—
ProductHCID 86654558HCID 86654558—

Reaction Steps

1-{5-[1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-4-oxo-4,5-dihydro-thiazol-2-yl}-pyrrolidine-2-(R)-carboxylic acid was prepared from 5-[1-(2,4-bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-methylsulfanyl-thiazol-4-one and pyrrolidine-2-(R)-carboxylic acid following General Procedure C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399681B2
Source datasetuspto-grants-2013_03
ORD IDord-cbc47d7d81e043dabcdbe3f0f982354f
Source noteuspto-grants-2013_03