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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1949387Generated: November 1, 2026

D-Proline → HCID 67240542, compound

https://huagongshe.com/reaction/1949387

Reaction equation

Participants

RoleNameHCIDCharge
ReactantD-ProlineHCID 8988—
Reactant5-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-oneHCID 67240123—
ProductHCID 67240542HCID 67240542—

Reaction Steps

1-{5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-4-oxo-4,5-dihydro-thiazol-2-yl}-pyrrolidine-2-(R)-carboxylic acid was prepared from 5-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-one and pyrrolidine-2-(R)-carboxylic acid following General Procedure C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399681B2
Source datasetuspto-grants-2013_03
ORD IDord-4d9debbdb98341929f13c1ef4f876675
Source noteuspto-grants-2013_03