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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1949409Generated: October 30, 2026

(1S,4S)-tert-butyl 2,5-diazabicyclo(2.2.1)heptane-2-carboxylate → HCID 86654568, compound

https://huagongshe.com/reaction/1949409

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1S,4S)-tert-butyl 2,5-diazabicyclo(2.2.1)heptane-2-carboxylateHCID 2760898—
Reactant5-[1-(2,4-bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]2-methylsulfanyl-thiazol-4-oneHCID 86654543—
ProductHCID 86654568HCID 86654568—

Reaction Steps

5-{5-[1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-4-oxo-4,5-dihydro-thiazol-2-yl}-2,5-diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester was prepared from 5-[1-(2,4-bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-methylsulfanyl-thiazol-4-one and 2,5-diaza-bicyclo[2.2.1]heptane-2-carboxylic acid tert-butyl ester following General Procedure C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399681B2
Source datasetuspto-grants-2013_03
ORD IDord-d1a23c00f92743248fbf2a8ccb5af023
Source noteuspto-grants-2013_03