1-Tert-butylpiperazine → HCID 67243026, compound

HRID 1949420Notes

Reaction equation

HRID 1949420 reaction equation
[Cl:1][C:2]1[CH:27]=[CH:26][C:5]([CH2:6][N:7]2[C:15]3[C:10](=[CH:11][C:12]([CH:16]=[C:17]4[S:21][C:20](SCC)=[N:19][C:18]4=[O:25])=[CH:13][CH:14]=3)[CH:9]=[N:8]2)=[C:4]([C:28]([F:31])([F:30])[F:29])[CH:3]=1.[C:32]([N:36]1[CH2:41][CH2:40][NH:39][CH2:38][CH2:37]1)([CH3:35])([CH3:34])[CH3:33]>>[C:32]([N:36]1[CH2:41][CH2:40][N:39]([C:20]2[S:21][C:17](=[CH:16][C:12]3[CH:11]=[C:10]4[C:15](=[CH:14][CH:13]=3)[N:7]([CH2:6][C:5]3[CH:26]=[CH:27][C:2]([Cl:1])=[CH:3][C:4]=3[C:28]([F:31])([F:29])[F:30])[N:8]=[CH:9]4)[C:18](=[O:25])[N:19]=2)[CH2:38][CH2:37]1)([CH3:35])([CH3:34])[CH3:33]

Participants

3

Reactant 2

HCID 35305721-Tert-butylpiperazineHCID 672401235-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-one

Product 1

HCID 67243026HCID 67243026, compound

Procedure

2-(4-tert-Butyl-piperazin-1-yl)-5-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-thiazol-4-one was prepared from 5-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-one and 1-tert-butyl-piperazine following General Procedure C.

Sources & evidence

ORD record
ord-7f2edae1b2a24082b27e26081e27cd6c
Source dataset
uspto-grants-2013_03
Patent number
US08399681B2

Reaction notes

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