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(R)-2-Hydroxymethyl-piperazine-1-carboxylic acid tert-butyl ester → HCID 86654582、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (R)-2-Hydroxymethyl-piperazine-1-carboxylic acid tert-butyl ester | HCID 24820219 | — |
| 反応物 | 5-[1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-one | HCID 86654540 | — |
| 生成物 | HCID 86654582 | HCID 86654582 | — |
反応手順
4-{5-[1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-4-oxo-4,5-dihydro-thiazol-2-yl}-2-(R)-hydroxymethyl-piperazine-1-carboxylic acid tert-butyl ester was prepared from 5-[1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-one and (2R)-Hydroxymethyl-piperazine-1-carboxylic acid tert-butyl ester following General Procedure C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08399681B2 |
| 出典データセット | uspto-grants-2013_03 |
| ORD ID | ord-15da8f55ec4c417794bc977519110d13 |
| 出典メモ | uspto-grants-2013_03 |