HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholin-2-ylmethanol → 5-[1-(4-Fluoro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-((2S)-2-hydroxymethyl-morpholin-4-yl)-thiazol-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholin-2-ylmethanol | HCID 3497988 | — |
| Reactant | 5-[1-(4-Fluoro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-propylsulfanyl-thiazol-4-one | HCID 67240132 | — |
| Product | 5-[1-(4-Fluoro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-((2S)-2-hydroxymethyl-morpholin-4-yl)-thiazol-4-one | HCID 67241301 | — |
Reaction Steps
5-[1-(4-Fluoro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-((2S)-2-hydroxymethyl-morpholin-4-yl)-thiazol-4-one was prepared from 5-[1-(4-Fluoro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-propylsulfanyl-thiazol-4-one and (2S) Morpholin-2-yl-methanol following General Procedure B.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399681B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-b53f37fbc102411e8cc3f902e5554ae3 |
| Source note | uspto-grants-2013_03 |