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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1949530Generated: October 31, 2026

Piperazine, 1,3-dimethyl-, (3R)-rel- → HCID 86674124, compound

https://huagongshe.com/reaction/1949530

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperazine, 1,3-dimethyl-, (3R)-rel-HCID 59768148—
Reactant5-[1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-oneHCID 86654540—
ProductHCID 86674124HCID 86674124—

Reaction Steps

5-({1-[2,4-Bis(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-2-(2-(R),4-dimethylpiperazin-1-yl)-1,3-thiazol-4(5H)-one was prepared from 5-[1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-one and 1,3-(R)-Dimethyl-piperazine following general procedure C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399681B2
Source datasetuspto-grants-2013_03
ORD IDord-841f7229fd0c41bf869e1cfb0e2de7ac
Source noteuspto-grants-2013_03