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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1949541Generated: October 30, 2026

rel-(2R,6S)-4-(3-Azetidinyl)-2,6-dimethylmorpholine → HCID 86654604, compound

https://huagongshe.com/reaction/1949541

Reaction equation

Participants

RoleNameHCIDCharge
Reactantrel-(2R,6S)-4-(3-Azetidinyl)-2,6-dimethylmorpholineHCID 66592027—
Reactant5-[1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-oneHCID 86654540—
ProductHCID 86654604HCID 86654604—

Reaction Steps

5-({1-[2,4-Bis(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-2-[3-(2,6-cis-dimethylmorpholin-4-yl)azetidin-1-yl]-1,3-thiazol-4(5H)-one was prepared from 5-[1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-one and 4-Azetidin-3-yl-2,6-(cis)-dimethyl-morpholine following General Procedure C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399681B2
Source datasetuspto-grants-2013_03
ORD IDord-eb799a7030444860867751a8f6a993a2
Source noteuspto-grants-2013_03