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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1949579Generated: November 1, 2026

(3R)-(+)-3-(Dimethylamino)pyrrolidine → HCID 86654617, compound

https://huagongshe.com/reaction/1949579

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3R)-(+)-3-(Dimethylamino)pyrrolidineHCID 2758521—
Reactant5-[1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-oneHCID 86654540—
ProductHCID 86654617HCID 86654617—

Reaction Steps

5-({1-[2,4-Bis(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-2-[(3R)-3-(dimethylamino)pyrrolidin-1-yl]-1,3-thiazol-4(5H)-one was prepared from 5-[1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-one and (3R)Dimethyl-pyrrolidin-3-yl-amine following General Procedure C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399681B2
Source datasetuspto-grants-2013_03
ORD IDord-847d36e1d0864a9db3a9e5f127621435
Source noteuspto-grants-2013_03