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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1949592Generated: October 30, 2026

4-hydroxypiperidine-4-carboxylic Acid → HCID 86654624, compound

https://huagongshe.com/reaction/1949592

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-hydroxypiperidine-4-carboxylic AcidHCID 4437198—
Reactant5-[1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-oneHCID 86654540—
ProductHCID 86654624HCID 86654624—

Reaction Steps

1-[5-({1-[2,4-Bis(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-4-oxo-4,5-dihydro-1,3-thiazol-2-yl]-4-hydroxypiperidine-4-carboxylic acid was prepared from 5-[1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-one and 4-Hydroxy-piperidine-4-carboxylic acid following General Procedure C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399681B2
Source datasetuspto-grants-2013_03
ORD IDord-55d2439e987d40a7b28ebe4a46516865
Source noteuspto-grants-2013_03