Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1949605Generated: October 27, 2026

2-(Chloromethyl)-3-(trifluoromethyl)pyridine → 1-(3-Trifluoromethyl-pyridin-2-ylmethyl)-1H-indazole-5-carbaldehyde

https://huagongshe.com/reaction/1949605

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Chloromethyl)-3-(trifluoromethyl)pyridineHCID 18361737—
Reactant1H-Indazole-5-carboxaldehydeHCID 21250644—
Product1-(3-Trifluoromethyl-pyridin-2-ylmethyl)-1H-indazole-5-carbaldehydeHCID 86654628—

Reaction Steps

1-(3-Trifluoromethyl-pyridin-2-ylmethyl)-1H-indazole-5-carbaldehyde was prepared from 1H-Indazole-5-carbaldehyde and 2-Chloromethyl-3-trifluoromethyl-pyridine following General Procedure A.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399681B2
Source datasetuspto-grants-2013_03
ORD IDord-0a66159cd68645bf9025b30480ae3241
Source noteuspto-grants-2013_03