HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 2-Bromo-4,5-dihydro-6-oxa-1-thia-benzo[e]azulene-9-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 4,5-Dihydro-6-oxa-1-thia-benzo[e]azulene-9-carbonitrile | HCID 56834154 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-Bromo-4,5-dihydro-6-oxa-1-thia-benzo[e]azulene-9-carbonitrile | HCID 56834155 | — |
Reaction Steps
To a solution of 4,5-dihydro-6-oxa-1-thia-benzo[e]azulene-9-carbonitrile (4.58 g) in dichloromethane (30 mL) and acetic acid (30 mL) was added N-bromosuccinimide (3.95 g) and the reaction stirred at room temperature for 16 h. Water (100 mL) was then added and the solid collected by filtration and air-dried to give 2-bromo-4,5-dihydro-6-oxa-1-thia-benzo[e]azulene-9-carbonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399690B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-14f8c7017477409a9bd99c71cf27fbf4 |
| Source note | uspto-grants-2013_03 |