HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methyl-1H-pyrazole-4-boronic acid pinacol ester → HCID 178434496, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methyl-1H-pyrazole-4-boronic acid pinacol ester | HCID 17750270 | — |
| Reactant | 8-bromo-N-(2-chlorophenyl)-N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamide | HCID 44242427 | — |
| Product | HCID 178434496 | HCID 178434496 | — |
Reaction Steps
Following the procedure in Example 93, 8-bromo-N-(2-chlorophenyl)-N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamide was coupled with 5-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole to give 318. MS (ESI) 450.1
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399690B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-6f4088272dfb412c8e50093a3288b00e |
| Source note | uspto-grants-2013_03 |