HCID 23087108, compound → HCID 57934534, compound

HRID 1949996Notes

Reaction equation

HRID 1949996 reaction equation
NC1(C[O:8]C2C=CC(C#N)=CC=2)CCCC1.[CH3:17][N:18]([CH3:34])[C:19]1([CH2:24][O:25][C:26]2[CH:33]=[CH:32][C:29]([C:30]#N)=[CH:28][CH:27]=2)[CH2:23][CH2:22][CH2:21][CH2:20]1>>[CH3:17][N:18]([CH3:34])[C:19]1([CH2:24][O:25][C:26]2[CH:33]=[CH:32][C:29]([CH:30]=[O:8])=[CH:28][CH:27]=2)[CH2:23][CH2:22][CH2:21][CH2:20]1

Participants

3

Reactant 2

HCID 23087108HCID 23087108, compoundHCID 23087111HCID 23087111, compound

Product 1

HCID 57934534HCID 57934534, compound

Procedure

Synthesized from 4-(1-aminocyclopentylmethoxy)benzonitrile according to an analogous synthetic method to Preparation Example 18, 4-(1-dimethylaminocyclopentylmethoxy)benzonitrile (1.2 g) was used according to an analogous synthetic method to Preparation Example 16 to provide the title compound (1.2 g).

Workup

  1. customwas used according to an analogous synthetic method to Preparation Example 16

Sources & evidence

ORD record
ord-5abf4df971024ef98a31c50488dbf429
Source dataset
uspto-grants-2013_03
Patent number
US08399520B2

Reaction notes

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