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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1950064Generated: November 1, 2026

N-ethyl-N-[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]-2-phenylacetamide → 6-[2-(Ethylphenethylamino)-4-hydroxyphenyl]-5,6,7,8-tetrahydronaphthalen-2-ol

https://huagongshe.com/reaction/1950064

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-ethyl-N-[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]-2-phenylacetamideHCID 57933908—
ReactantEthyl[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]phenethylamineHCID 66626971—
Product6-[2-(Ethylphenethylamino)-4-hydroxyphenyl]-5,6,7,8-tetrahydronaphthalen-2-olHCID 57934343—

Reaction Steps

Synthesized from N-ethyl-N-[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]-2-phenylacetamide according to an analogous synthetic method to Example 337 described below, ethyl[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]phenethylamine (137 mg) was used according to an analogous synthetic method to Example 111 described below to provide the title compound (77 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399520B2
Source datasetuspto-grants-2013_03
ORD IDord-e3b99b3dc676401e9275fe505124676d
Source noteuspto-grants-2013_03