HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxy-8,9-dihydro-5H-benzo[7]annulen-6(7H)-one → 3-Methoxy-8-(4-methoxy-2-nitrophenyl)-6,7-dihydro-5H-benzocycloheptene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxy-8,9-dihydro-5H-benzo[7]annulen-6(7H)-one | HCID 12369177 | — |
| Reactant | Tributyl(4-methoxy-2-nitrophenyl)tin | HCID 23087474 | — |
| Reactant | HCID 86605238 | HCID 86605238 | — |
| Product | 3-Methoxy-8-(4-methoxy-2-nitrophenyl)-6,7-dihydro-5H-benzocycloheptene | HCID 66626968 | — |
Reaction Steps
Synthesized from 2-methoxy-5,7,8,9-tetrahydrobenzocyclohepten-6-one according to an analogous synthetic method to Preparation Example 82, 2-methoxy-8,9-dihydro-7H-benzocyclohepten-6-yl trifluoromethanesulfonate (3.0 g) and tributyl(4-methoxy-2-nitrophenyl)tin (10.8 g) were used according to an analogous synthetic method to Preparation Example 77 to provide the title compound (2.8 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399520B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-94a96d35058b421eae3be8ced5fea4a9 |
| Source note | uspto-grants-2013_03 |