HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannane, tributyl(2-nitrophenyl)- → 2-(2-Methoxy-6,7,8,9-tetrahydro-5H-benzocyclohepten-6-yl)phenylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannane, tributyl(2-nitrophenyl)- | HCID 11338886 | — |
| Reactant | HCID 69775434 | HCID 69775434 | — |
| Reactant | 2-methoxy-8,9-dihydro-7H-benzocyclohepten-6-yl trifluoromethanesulfonate | HCID 86605238 | — |
| Product | 2-(2-Methoxy-6,7,8,9-tetrahydro-5H-benzocyclohepten-6-yl)phenylamine | HCID 57934283 | 65% |
Reaction Steps
Synthesized from 2-methoxy-8,9-dihydro-7H-benzocyclohepten-6-yl trifluoromethanesulfonate and tributyl(2-nitrophenyl)tin according to an analogous synthetic method to Preparation Example 77, 3-methoxy-8-(2-nitrophenyl)-6,7-dihydro-5H-benzocycloheptene (850 mg) was used according to an analogous synthetic method to Example 30 to provide the title compound (500 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399520B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-b8da094e4ff94ee0bcc2acef7758af78 |
| Source note | uspto-grants-2013_03 |