HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-3-nitroanisole → 5-Methoxy-2-(6-methoxy-3,3-dimethyl-1,2,3,4-tetrahydronaphthalen-2-yl)phenylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-3-nitroanisole | HCID 79288 | — |
| Reactant | 7-Methoxy-3-(4-methoxy-2-nitrophenyl)-2,2-dimethyl-1,2-dihydronaphthalene | HCID 23087432 | — |
| Reactant | 3-Bromo-7-methoxy-2,2-dimethyl-1,2-dihydronaphthalene | HCID 23087570 | — |
| Product | 5-Methoxy-2-(6-methoxy-3,3-dimethyl-1,2,3,4-tetrahydronaphthalen-2-yl)phenylamine | HCID 23087135 | 86% |
Reaction Steps
Synthesized from 3-bromo-7-methoxy-2,2-dimethyl-1,2-dihydronaphthalene and 4-bromo-3-nitroanisole according to an analogous synthetic method to Preparation Example 107 described below, 7-methoxy-3-(4-methoxy-2-nitrophenyl)-2,2-dimethyl-1,2-dihydronaphthalene (1.9 g) was used according to an analogous synthetic method to Example 30 to provide the title compound (1.5 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399520B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-a0d34beee78d4748b17c21b27ac75f08 |
| Source note | uspto-grants-2013_03 |