HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-2-nitrobenzene → 2-(6-Methoxy-3,3-dimethyl-3,4-dihydronaphthalen-2-yl)phenylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-2-nitrobenzene | HCID 11341 | — |
| Reactant | 7-Methoxy-2,2-dimethyl-3-(2-nitrophenyl)-1,2-dihydronaphthalene | HCID 23087552 | — |
| Reactant | 3-Bromo-7-methoxy-2,2-dimethyl-1,2-dihydronaphthalene | HCID 23087570 | — |
| Product | 2-(6-Methoxy-3,3-dimethyl-3,4-dihydronaphthalen-2-yl)phenylamine | HCID 23087497 | 53.5% |
Reaction Steps
Synthesized from 3-bromo-7-methoxy-2,2-dimethyl-1,2-dihydronaphthalene and 1-bromo-2-nitrobenzene according to an analogous synthetic method to Preparation Example 107 described below, 7-methoxy-2,2-dimethyl-3-(2-nitrophenyl)-1,2-dihydronaphthalene (1.4 g) was used according to an analogous synthetic method to Example 57 to provide the title compound (676 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399520B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-91431b1bdb2e40da9e69165d29a355f0 |
| Source note | uspto-grants-2013_03 |