HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-3,4-(methylenedioxy)benzene → 5-(6-Benzyloxy-3,4-dihydronaphthalen-2-yl)-6-nitrobenzo[1,3]dioxole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-3,4-(methylenedioxy)benzene | HCID 75831 | — |
| Reactant | 5-Bromo-6-nitro-1,3-benzodioxole | HCID 1519756 | — |
| Reactant | 3-Bromo-1,2-dihydro-7-(phenylmethoxy)naphthalene | HCID 23087420 | — |
| Product | 5-(6-Benzyloxy-3,4-dihydronaphthalen-2-yl)-6-nitrobenzo[1,3]dioxole | HCID 66627064 | 10.9% |
Reaction Steps
Synthesized from 4-bromo-1,2-(methylenedioxy)benzene according to an analogous synthetic method to Preparation Example 108, 5-bromo-6-nitrobenzo[1,3]dioxole (9.4 g) and 7-benzyloxy-3-bromo-1,2-dihydronaphthalene (6.0 g) were used according to an analogous synthetic method to Preparation Example 107 to provide the title compound (834 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399520B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-3f0e7b19157640ad9eb69707ada8842e |
| Source note | uspto-grants-2013_03 |