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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1950122Generated: October 26, 2026

6-Methoxy-alpha-tetralone → 7-Methoxy-3-(2-methyl-6-nitrophenyl)-1,2-dihydronaphthalene

https://huagongshe.com/reaction/1950122

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxy-alpha-tetraloneHCID 14112—
Reactant2-Bromo-3-nitrotolueneHCID 231828—
Reactant3-Bromo-7-methoxy-1,2-dihydronaphthaleneHCID 11601147—
Product7-Methoxy-3-(2-methyl-6-nitrophenyl)-1,2-dihydronaphthaleneHCID 23087267—

Reaction Steps

Synthesized from 6-methoxy-1-tetralone according to an analogous synthetic method to Preparation Example 106, 3-bromo-7-methoxy-1,2-dihydronaphthalene (2.7 g) and 2-bromo-3-nitrotoluene (4.8 g) were used according to an analogous synthetic method to Preparation Example 107 to provide 7-methoxy-3-(2-methyl-6-nitrophenyl)-1,2-dihydronaphthalene (925 mg). This compound (920 mg) was used according to an analogous synthetic method to Example 30 to provide the title compound (740 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399520B2
Source datasetuspto-grants-2013_03
ORD IDord-35c1cbcb75c54cbc9bbce3a2ce66e5b4
Source noteuspto-grants-2013_03