HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-Piperidin-1-ylethoxy)benzoyl chloride hydrochloride → [5-Methoxy-2-(6-methoxy-3,4-dihydronaphthalen-2-yl)phenyl][4-(2-piperidin-1-ylethoxy)benzyl]amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-Piperidin-1-ylethoxy)benzoyl chloride hydrochloride | HCID 16111922 | — |
| Reactant | 5-Methoxy-2-(6-methoxy-3,4-dihydronaphthalen-2-yl)phenylamine | HCID 23087218 | — |
| Product | [5-Methoxy-2-(6-methoxy-3,4-dihydronaphthalen-2-yl)phenyl][4-(2-piperidin-1-ylethoxy)benzyl]amine | HCID 57934431 | 18.7% |
Reaction Steps
Synthesized from 5-methoxy-2-(6-methoxy-3,4-dihydronaphthalen-2-yl)phenylamine (341 mg) and 4-(2-piperidin-1-ylethoxy)benzoyl chloride hydrochloride (990 mg) according to an analogous synthetic method to Example 110, the title compound (113 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399520B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-c5340423ae48404495be576bec5b0335 |
| Source note | uspto-grants-2013_03 |