HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-(4-Bromo-2-fluorophenoxy)ethyl)piperidine → HCID 57934277, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-(4-Bromo-2-fluorophenoxy)ethyl)piperidine | HCID 23087072 | — |
| Reactant | 5-Methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenylamine | HCID 23087205 | — |
| Reactant | HCID 66627151 | HCID 66627151 | — |
| Product | HCID 57934277 | HCID 57934277 | 52.9% |
Reaction Steps
Synthesized from 5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenylamine and 1-[2-(4-bromo-2-fluorophenoxy)ethyl]piperidine according to an analogous synthetic method to Example 116, [3-fluoro-4-(2-piperidin-1-ylethoxy)phenyl][5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]amine (84 mg) was used according to an analogous synthetic method to Example 111 to provide the title compound (42 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399520B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-7f56033f71f84ddaac1cb13af9679ee7 |
| Source note | uspto-grants-2013_03 |